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The Lord shall preserve thee from all evil - Spiritual and corporeal, natural and moral.

He shall preserve thy soul - Take care of thy life, and take care of thy soul.

The Lord shall preserve thee from all evil - This is an advance of the thought. The psalmist had in the previous verses specified some particular evils from which he says God would keep those who put their trust in him. He now makes the remark general, and says that God would not only preserve from these particular evils, but would keep those who trusted in him from all evil: he would be their Protector in all the perils of life.

He shall preserve thy soul - Thy life. See Psalm 41:2; Psalm 97:10.

It was when the nation was racked with internal strife, when the calm, God-fearing counsel of Samuel seemed to be most needed, that God gave His aged servant rest. Bitter were the reflections of the people as they looked upon his quiet resting place, and remembered their folly in rejecting him as their ruler; for he had had so close a connection with Heaven that he seemed to bind all Israel to the throne of Jehovah. It was Samuel who had taught them to love and obey God; but now that he was dead, the people felt that they were left to the mercies of a king who was joined to Satan, and who would divorce the people from God and heaven. PP 664.1

David could not be present at the burial of Samuel, but he mourned for him as deeply and tenderly as a faithful son could mourn for a devoted father. He knew that Samuel's death had broken another bond of restraint from the actions of Saul, and he felt less secure than when the prophet lived. While the attention of Saul was engaged in mourning for the death of Samuel, David took the opportunity to seek a place of greater security; so he fled to the wilderness of Paran. It was here that he composed the one hundred and twentieth and twenty-first psalms. In these desolate wilds, realizing that the prophet was dead, and the king was his enemy, he sang: PP 664.2

“My help cometh from the Lord,
Which made heaven and earth.
He will not suffer thy foot to be moved:
He that keepeth thee will not slumber.
Behold, He that keepeth Israel
Shall neither slumber nor sleep....
The Lord shall preserve thee from all evil:
He shall preserve thy soul.
The Lord shall preserve thy going out and thy
coming in
From this time forth, and even forevermore.” PP 664.3

Behold, he that keepeth Israel shall neither slumber nor sleep. The Lord is thy keeper: the Lord is thy shade upon thy right hand.... The Lord shall preserve thee from all evil: he shall preserve thy soul. Psalm 121:4-7. TMK 143.1

In that day, multitudes will desire the shelter of God's mercy which they have so long despised. “Behold, the days come, saith the Lord God, that I will send a famine in the land, not a famine of bread, nor a thirst for water, but of hearing the words of the Lord: and they shall wander from sea to sea, and from the north even to the east, they shall run to and fro to seek the word of the Lord, and shall not find it.” Amos 8:11, 12. GC 629.1

The people of God will not be free from suffering; but while persecuted and distressed, while they endure privation and suffer for want of food they will not be left to perish. That God who cared for Elijah will not pass by one of His self-sacrificing children. He who numbers the hairs of their head will care for them, and in time of famine they shall be satisfied. While the wicked are dying from hunger and pestilence, angels will shield the righteous and supply their wants. To him that “walketh righteously” is the promise: “Bread shall be given him; his waters shall be sure.” “When the poor and needy seek water, and there is none, and their tongue faileth for thirst, I the Lord will hear them, I the God of Israel will not forsake them.” Isaiah 33:15, 16; 41:17. GC 629.2

“Although the fig tree shall not blossom, neither shall fruit be in the vines; the labor of the olive shall fail, and the fields shall yield no meat; the flock shall be cut off from the fold, and there shall be no herd in the stalls;” yet shall they that fear Him “rejoice in the Lord” and joy in the God of their salvation. Habakkuk 3:17, 18. GC 629.3

The Lord is thy keeper: the Lord is thy shade upon thy right hand. The sun shall not smite thee by day, nor the moon by night. The Lord shall preserve thee from all evil: he shall preserve thy soul. Psalm 121:5-7. RC 372.1