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Strangers are risen up against me - The Ziphites.

And oppressors - Saul, his courtiers, and his army.

They have not set God before them - It is on no religious account, nor is it to accomplish any end, on which they can ask the blessing of God.

Selah - This is true.

For strangers are risen up against me - That is, foreigners; those of another nation or land. Saul and his friends who sought the life of David were his own countrymen; these persons who sought go betray him were another people. They attempted to gain the favor of Saul, or to secure a reward from him, by betraying to him an innocent man whom he was persecuting.

And oppressors seek after my soul - Seek after my life. The word here rendered “oppressors” means people of violence; the proud; the haughty; persecutors; tyrants. The word properly denotes those who exert their power in an arbitrary manner, or not under the sanction of law.

They have not set God before them - They do not act as in the presence of God. They do not regard his authority. See the notes at Psalm 36:1. The word “Selah” here merely marks a musical pause. It indicates nothing in regard to the sense.

God is faithful, though men are not to be trusted, and it is well for us it is so. David has no other plea to depend upon than God's name, no other power to depend upon than God's strength, and these he makes his refuge and confidence. This would be the effectual answer to his prayers. Looking unto David, betrayed by the men of Judah, and to Jesus, betrayed by one of his apostles, what can we expect from any who have not set God before them, save ingratitude, treachery, malice, and cruelty? What bonds of nature, or friendship, or gratitude, or covenant, will hold those that have broken through the fear of God? Selah; Mark this. Let us set God before us at all times; for if we do not, we are in danger of despair.